Medical therapy

Surgical and percutaneous options for post-infarction VSD improve survival compared to medical treatment

September 18, 2022 2 minute read Source/Disclosures Published by: Source: Giblett J, et al. Late-breaking science in structural heart disease: session II, in collaboration with The European Journal of the Heart/Eurointervention. Presented at: TCT Scientific Symposium; September 16-19, 2022; Boston (hybrid meeting). Disclosures: Giblett does not report any relevant financial information. ADD A SUBJECT TO […]

Medical therapy

Dapagliflozin Effects Based on HFC Medical Therapy Score

Patients with heart failure (HF) and reduced ejection fraction have been researched by the Heart Failure Collaboratory (HFC), resulting in the creation of a score that takes into account the times of the types and amounts of drugs recommended by clinical guidelines. This score has the potential to be used to determine whether or not […]

Medical therapy

NEJM: Study compares PCI to medical therapy to reduce death or hospitalization from heart failure

August 30 NEJM: Study compares PCI to medical therapy to reduce death or hospitalization from heart failure MedicalResearch.com Interview with: Dr. Morgan Dr. Holly Morgan MB, B.Ch.Clinical Researcher and Investigator REVIVEDKing’s College London MedicalResearch.com: What is the background of this study? Answer: Coronary artery disease is the most common cause of heart failure. While individually […]

Medical therapy

Clinical outcomes in patients with HFrEF related to titration of medical therapy

In patients with chronic heart failure with reduced ejection fraction (HFrEF), characteristics such as blood pressure and recent hospitalization status are associated with a likelihood of escalation and de-escalation of inhibitor therapy. angiotensin converting enzyme (ACE) and β-blocker. These findings were published in the American Journal of the Heart. An analysis was conducted and included […]

Medical therapy

Catheter ablation VS medical therapy for atrial fibrillation

Observational studies implicated that catheter ablation may be safe and effective for treating atrial fibrillation in young and old people. It had not been studied in a large randomized experiment. The report summarizes the results of the CABANA trial by age at enrollment (catheter ablation versus antiarrhythmic drug therapy for atrial fibrillation). Patients with atrial […]

Medical therapy

Estimated benefit of combined medical therapy in heart failure with mildly reduced and preserved ejection fraction

Disclosures Dr. Vaduganathan has received research grants or served on advisory boards for American Regent, Amgen, AstraZeneca, Bayer AG, Baxter Healthcare, Boehringer Ingelheim, Cytokinetics, Lexicon Pharmaceuticals, Novartis, Pharmacosmos, Relypsa, Roche Diagnostics, and Sanofi; has had speaking engagements with Novartis and Roche Diagnostics; and participates in clinical trial committees for studies sponsored by Galmed, Novartis, Bayer […]

Medical therapy

Economic advantages of surgery compared to medical therapy in drug-resistant epilepsy

An analysis of real-world data shows that the long-term economic benefits of surgery for drug-resistant epilepsy outweigh the upfront costs of surgery compared to medical treatment. “Epilepsy surgery has been shown to improve seizure control in children with drug-resistant epilepsy, and the American Academy of Neurology recommends surgery for the treatment of drug-resistant focal epilepsy […]

Medical therapy

Recent advances in the medical treatment of urological cancers

This article was originally published here Front oncol. 2022 Apr 4;12:746922. doi: 10.3389/fonc.2022.746922. eCollection 2022. ABSTRACT The mainstay of medical treatment has been tyrosine kinase (TKI) inhibitors for renal cell cancer (RCC), cytotoxic chemotherapy for urothelial cancer (UC), and androgen deprivation therapy for prostate cancer . These therapeutic modalities still play an important role in […]

Medical therapy

Impact of catheter ablation versus medical therapy on cognitive function in atrial fibrillation: a systematic review

This article was originally published here J Interv Card Electrophysiol. 2022 April 5. doi: 10.1007/s10840-022-01196-y. Online ahead of print. ABSTRACT OBJECTIVE: Atrial fibrillation is associated with an increased risk of cognitive impairment. It is unclear whether restoring sinus rhythm with catheter ablation can modify this risk. We performed a systematic review of studies comparing cognitive […]

Medical therapy

Personalized digital alert enhances guideline-directed medical therapy for heart failure

According to a study presented at the American College of Cardiology’s 71st Annual scientific session. The study, which met its primary endpoint of an increase in the number of guideline-directed medical therapy (GDMT) classes prescribed 30 days after randomization, is the first randomized trial to show significant improvements in use of GDMT for heart failure […]

Medical therapy

Medical Therapy and Guideline Updates for Peripheral Arterial Disease

Several approaches can be taken to optimize medical treatment in patients with PAD. A session presented at the American College of Cardiology’s 2022 Scientific Sessions on Treatments for Peripheral Arterial Disease (PAD) highlights the therapy’s promising future for cardiovascular health. Connie Ng Hess, MD, MHS, provided updates on PCSK9 (PCKS9i) inhibitors and anticoagulant treatments as […]

Medical therapy

Patiromer enables optimal medical therapy, prevention of hyperkalemia in HFrEF

April 03, 2022 3 minute read Source/Disclosures Published by: Source: Butler J, et al. Joint American College of Cardiology/New England Journal of Medicine Last minute tests. Presented at the American College of Cardiology Scientific Session; April 2-4, 2022; Washington, DC (hybrid meeting). Disclosures: The study was funded by Vifor Pharma. Butler reports financial […]

Medical therapy

Outpatient Management of Guideline-Directed Medical Therapy for Heart Failure Using Telehealth: A Comparison of Office, Video, and Telephone Visits

This article was originally published here Card J Failed Mar 19, 2022: S1071-9164(22)00449-3. doi:10.1016/j.cardfail.2022.02.016. Online ahead of print. ABSTRACT BACKGROUND: There are limited data regarding the management of guideline-directed medical therapy (GDMT) for heart failure with reduced ejection fraction (HFrEF) with virtual visits versus office visits. We sought to compare GDMT modifications (angiotensin converting enzyme […]

Medical therapy

Simplifying the medical treatment of glaucoma for our patients

Adherence to lifelong glaucoma treatment demands a lot from our patients. They must be able to afford and acquire their medications, remember the daily dosing schedule, be able to tolerate the drops well enough not to skip doses, and be physically successful in instilling the drops. That’s a lot to ask of patients, especially as […]

Medical therapy

Endoscopic sinus surgery with effective medical therapy for chronic rhinosinusitis with nasal polyps

Patients with chronic rhinosinusitis with nasal polyps were found to benefit more from the combination of endoscopic sinus surgery and medical treatment compared to medical treatment alone, although the minimal clinically important difference was not reached. According to the results of a study published in Respiratory Medicine The Lancet. Typically performed when patients with CRSwNP […]

Medical therapy

Bortezomib-induced reversible cardiomyopathy: cured with guideline-compliant medical treatment

This article was originally published here Cureus. 2021 Dec 9;13(12):e20295. doi: 10.7759/cureus.20295. eCollection 2021 Dec. ABSTRACT Bortezomib (BTZ) is a proteasome inhibitor (PI) used for the treatment of several hematological malignancies, including multiple myeloma (MM) and various lymphomas, including mantle cell lymphoma (MCL). It acts via disruption of the ubiquitin-proteasome pathway which plays a major […]

Medical therapy

DOMINIC LAWSON: I received the same pseudo-medical therapy as Djokovic and I recognize a waterfall when I see it

What’s the difference between how the Romans punished Jesus Christ and how the Australian government treats the world’s best male tennis player, 34-year-old Novak Djokovic? None, according to his father, Srdjan Djokovic. Last week he said: “Jesus was crucified on the cross and everything was done to him, but he is still alive among us. […]

Medical therapy

Endoscopic sinus surgery with medical treatment versus medical treatment for chronic rhinosinusitis with nasal polyps: a multicenter, randomized, controlled trial

Fund Endoscopic sinus surgery (ESS) is a common operation in patients with chronic rhinosinusitis with nasal polyps (CRSwNP) when medical treatment alone is insufficient. No randomized controlled trials on the effectiveness of ESS have been published. Our aim was to assess the effectiveness of ESS plus medical treatment versus medical treatment alone in patients with […]

Medical therapy

optimal medical treatment in patients undergoing PVI

Persistent gaps in treatment practice remain for peripheral arterial disease (PAD) and atherosclerosis. Megan Lee, a fourth-year medical student at Yale School of Medicine, explores inconsistencies in the use of guideline-directed medical therapy after peripheral vascular intervention (PVI), a minimally invasive procedure that restores blood flow to the lower limbs. Published in the American Heart […]

Medical therapy

Oklahoma Regenerative Medical Therapy for Chronic Pain

Oklahoma City, USA, 07 Dec. 2021 (GLOBE NEWSWIRE) — The clinic’s recently updated treatment options reflect the increasing pace of medical breakthroughs and physicians’ focus on addressing the root causes of chronic pain; not just the symptoms. More details can be found at https://oklahomapaincenter.com/regeneration-therapy The Oklahoma Pain Center now recommends regenerative therapy for many of […]

Medical therapy

Patients with malignant glaucoma respond better to surgical treatment than to medical treatment

November 19, 2021 1 minute read Source/Disclosures Published by: Source: SL side. Treatment regimens for malignant glaucoma in the United States: analysis of the IRIS registry. Presented at the meeting of the American Academy of Ophthalmology; November 12-15, 2021; New Orleans. Disclosures: Cote does not report any relevant financial information. ADD A SUBJECT TO EMAIL […]

Medical therapy

Endocrine Society Reading Room | The limited efficacy of medical therapy in primary aldosteronism

Primary aldosteronism or primary hyperaldosteronism (PA) is the excessive production of aldosterone by the zona glomerulosa of the adrenal glands resulting in secondary hypertension. Although initially thought to be a rare cause of secondary hypertension with a prevalence of 4.3 mmol/L with a median reference range of 3.5 to 5.0 mmol/L). Of the 155 patients […]

Medical therapy

BLOG: Adjunctive Medical Therapy for Glaucoma: The Case Against Timolol

August 30, 2021 1 minute read Biography/Disclosures Published by: Disclosures: Aref reports having been a speaker for Aerie and receiving research support from Allergan. ADD A SUBJECT TO EMAIL ALERTS Receive an email when new articles are published on Please provide your email address to receive an email when new articles are published on . […]

Medical therapy

Cost Analyzes of Guideline-Directed Medical Therapy for the Treatment of HFrEF

According to a recent study published in Open JAMA Network.1 In a simulation model, researchers found that adding dapagliflozin to guideline-directed medical therapy (GDMT) has the potential to produce substantial clinical gains in this patient population with an acceptable increase in associated costs. This study found that at a willingness-to-pay threshold of $100,000 per quality-adjusted […]

Medical therapy

Electro-medical therapy can help treat intractable pain — Pain News Network

By Forest Tennant, PNN Columnist To maximize relief and recovery from intractable pain syndrome (IPS), it is advisable to use one or more electro-medical (EM) therapies. All individuals with IPS are strongly encouraged to try a variety of EM therapies, but only in addition or in addition to their current medical treatment. Electric current devices […]

Medical therapy

Adding dapagliflozin to effective and cost-effective medical treatment in HFrEF

August 16, 2021 2 minute read Source/Disclosures Published by: Disclosures: Isaza does not report any relevant financial information. Please see the study for relevant financial information from all other authors. ADD A SUBJECT TO EMAIL ALERTS Receive an email when new articles are published on Please provide your email address to receive an email when […]

Medical therapy

HRS 2021: Early VT catheter ablation beats medical treatment in patients at risk of sudden death

Roderick Tung Results from the PAUSE-SCD trial show a significant reduction in the risk of recurrent ventricular tachycardia (VT), cardiovascular hospitalization and death when catheter ablation is used as an early first-line treatment for patients with structural heart disease. The PAUSE-SCD trial is the first VT ablation trial to include patients with non-ischemic cardiomyopathy and […]

Medical therapy

Software to Guide Medical Therapy in CI Earns FDA Breakthrough Device Designation

ADD A SUBJECT TO EMAIL ALERTS Receive an email when new articles are published on Please provide your email address to receive an email when new articles are published on . ” data-action=”subscribe”> Subscribe We have not been able to process your request. Please try again later. If you continue to have this problem, please […]

Medical therapy

Optimizing medical therapy before clip repair for MR? ‘It’s hard’

Ensuring that patients receive maximum doses of heart failure treatments within guidelines is important, but also challenging, experts say. MIAMI, FL—A debate at TVT 2021 last week was supposed to focus on whether guideline-directed medical treatment should be tried at maximum tolerated doses before patients undergo transcatheter edge-to-edge repair (TEER ) for functional mitral regurgitation […]

Medical therapy

American Lung Association slams cigarette maker for acquiring medical inhalation treatment

Traco Power launches the TPP 300 series of power supplies Traco Power today announced its new TPP 300 series of 300W high density AC/DC power supplies. The 300 series is “available in open or fan-closed frame enclosures for a wide range of medical and applications where long-term reliability is critical and space is limited,” the […]

Medical therapy

In high-risk patients, optimal medical therapy confers a survival benefit after PCI, CABG

Source/Disclosures Published by: Disclosures: Boden, Gersh and Kawashima do not report any relevant financial information. Please see the study for relevant financial information from all other authors. ADD A SUBJECT TO EMAIL ALERTS Receive an email when new articles are published on Please provide your email address to receive an email when new articles are […]

Medical therapy

Semaglutide promises a ‘new era’ in the medical treatment of obesity

Source/Disclosures Published by: Source: Kaplan LM, et al. 3-CT-SY27. Presented at the American Diabetes Association Scientific Sessions, June 25-29, 2021 (virtual meeting). Disclosures: Kaplan reports that he has received consultant fees from Eli Lilly, Gelesis, GI Dynamics, Intellihealth, Johnson & Johnson, Novo Nordisk, Pfizer, Rhythm Pharmaceuticals, the NIH, and the Institute of Obesity and Nutrition. […]

Medical therapy

Metabolic surgery may be more effective than medical therapy for long-term control of type 2 diabetes

1. The 10-year remission rates were significantly higher for Roux-en-Y gastric bypass (RYGB) and biliopancreatic diversion (BPD) than for medical treatment. 2. Patients in the BPD and RYGB groups had fewer diabetes-related complications. Level of evidence assessment: 1 (Excellent) Overview of the study: Compared to conventional therapy, metabolic surgery results in significant short-term improvements in […]

Medical therapy

Medical therapy for endometriosis

But for women who fail such treatment due to progesterone resistance or intolerance to these compounds, other options are needed. The Belgian authors selected 11 articles published from a literature search in the PubMed and Embase electronic databases up to December 2020. The search was limited to peer-reviewed English full texts that reported data on […]

Medical therapy

Physical health, improved quality of life with bariatric surgery compared to medical therapy

April 26, 2021 1 minute read Source/Disclosures Published by: Source: Aminan A, et al. Patient-reported outcomes after metabolic surgery versus medical treatment for diabetes: insights from the STAMPEDE randomized trial. Presented at the American Surgical Association Annual Meeting; April 15-16, 2021 (virtual meeting). Disclosures: The authors report no relevant financial information. ADD A SUBJECT TO […]

Medical therapy

Many patients with ischemia do not receive optimal medical treatment

Less than half of patients whose peripheral vascular disease progressed to critical limb ischemia (CLI) received guideline-directed optimal medical treatment (GDMT), according to new research. GDMT is a comprehensive treatment plan designed to reduce the risk of cardiovascular events and improve blood circulation in the lower extremities. The authors collected recent data from the Vascular […]

Medical therapy

10-year RCT analysis suggests metabolic surgery is best medical therapy for T2D control

Data from a follow-up analysis of a randomized controlled trial suggest that weight loss surgery may be a more effective strategy than conventional medical therapy for the long-term control of type 2 diabetes. A 10-year follow-up to a trial comparing metabolic surgery to medical therapy in patients with type 2 diabetes, findings suggest metabolic surgery […]

Medical therapy

Medical therapy may prevent strokes in asymptomatic carotid stenosis

August 13, 2020 2 minute read Source/Disclosures Published by: Disclosures: Keyhani does not report any relevant financial information. Please see the study for relevant financial information from all other authors. ADD A SUBJECT TO EMAIL ALERTS Receive an email when new articles are published on Please provide your email […]

Medical therapy

Carotid endarterectomy and medical therapy show similar efficacy in asymptomatic carotid stenosis

1. In patients with asymptomatic carotid stenosis, there was no significant difference between the comparative effectiveness of initial medical therapy versus carotid endarterectomy. 2. The absolute risk reduction was found to be less than half the difference in risk of fatal and non-fatal strokes from carotid endarterectomy compared to 20 years ago. Level of evidence […]

Medical therapy

Medically clear: Medical therapy holds more promise than surgery… : Emergency medicine news

peritonsillar abscess: peritonsillar abscess Figure Figure Suction. To verify. Headlamp. To verify. Cetacaine. To verify. Gauze. To verify. Vaginal ultrasound probe. To verify. Needle and syringe. To verify. Sound familiar? It’s always been one of the trickiest procedures in the emergency department: Invasive drainage of angina requires a patient patient, a patient nurse and, if […]

Medical therapy

Improved medical therapy may lead to better results in the treatment of HFrEF

January 15, 2019 2 minute read ADD A SUBJECT TO EMAIL ALERTS Receive an email when new articles are published on Please provide your email address to receive an email when new articles are published on . ” data-action=”subscribe”> Subscribe We have not been able to process your request. Please try […]

Medical therapy

The real lesson of ORBITA: the remarkable power of medical therapy

Editor’s note: This post is part of a Health Affairs Blog series titled “ORBITA: Lessons From A Landmark Trial”, which focuses on the recent study finding that placement of a coronary stent did not improve exercise time compared to a placebo procedure in patients with angina pectoris and severe arterial stenosis who were receiving optimal […]

Medical therapy

EXCEL Deep Dive: Repeated revascularization, medical treatment and anemia all impact patient prognosis

A session devoted to the study of ICP versus CABG for left trunk disease provides an understanding of what influences clinical outcomes after the procedure. SAN DIEGO, CA—A deep dive into the EXCEL test at TCT 2018 provided some information on the impact of various clinical and patient characteristics, including postoperative medical treatment, baseline anemia, […]

Medical therapy

“Reasonable option” medical therapy vs surgery in Cushing’s disease

ADD A SUBJECT TO EMAIL ALERTS Receive an email when new articles are published on Please provide your email address to receive an email when new articles are published on . ” data-action=”subscribe”> Subscribe We have not been able to process your request. Please try again later. If you continue to […]

Medical therapy

Surgical treatment is better than medical treatment in severely obese adolescents with T2D

HealthDay News — According to a study published online in JAMA Pediatrics. Thomas H. Inge, MD, PhD, of the University of Colorado Denver in Aurora, and colleagues compared glycemic control in cohorts of severely obese adolescents with type 2 diabetes undergoing medical and surgical procedures. Data were obtained for participants in the Teen-Longitudinal Assessment of […]

Medical therapy

Optimal medical therapy with or without PCI for stable coronary artery disease

The authors’ affiliations are as follows: Western New York Veterans Affairs (VA) Healthcare Network and Buffalo General Hospital–SUNY, Buffalo, NY (WEB); South Texas Veterans Health Care System – Audie Murphy Campus, San Antonio, TX (RAO, PC); McMaster University Medical Center, Hamilton, ON, Canada (KKT); VA Cooperative Studies Program Coordinating Center, VA Connecticut Health System, West […]