Medical therapy

Optimal medical therapy with or without PCI for stable coronary artery disease

The authors’ affiliations are as follows: Western New York Veterans Affairs (VA) Healthcare Network and Buffalo General Hospital–SUNY, Buffalo, NY (WEB); South Texas Veterans Health Care System – Audie Murphy Campus, San Antonio, TX (RAO, PC); McMaster University Medical Center, Hamilton, ON, Canada (KKT); VA Cooperative Studies Program Coordinating Center, VA Connecticut Health System, West Haven, CT (PMH); Vanderbilt University Medical Center, Nashville (DJM); London Health Sciences Centre, London, ON, Canada (WJK); Foothills Hospital, Calgary, AB, Canada (MK); Hartford Hospital, Hartford, CT (MD); VA Cooperative Studies Program Clinical Research Pharmacy Coordinating Center, Albuquerque, NM (CLH); Saint Louis University, Saint Louis (BRC); Cedars-Sinai Medical Center, Los Angeles (LS, DSB); Montreal Heart Institute, Montreal (G. Gosselin); Sudbury Regional Hospital, Sudbury, ON, Canada (SN); Queen Elizabeth Health Sciences Centre, Halifax, NS, Canada (LMT); Mayo Clinic, Rochester, MN (G. Gau); Houston VA Medical Center, Houston (ASB); Lexington VA Medical Center, Lexington, KY (DCB); University of Michigan Medical Center, Ann Arbor (ERB); Mid America Heart Institute, Kansas City, MO (JAS); Vancouver Hospital and Health Sciences Centre, Vancouver, BC, Canada (GBJM); and Christiana Care Health System, Newark, DE (WSW).

Members of the COURAGE trial were: Drafting committee : W. Boden (Study Co-Chair), R. O’Rourke (Study Co-Chair) K. Teo (Study Co-Chair), P. Hartigan. W. Weintraub, D. Maron, J. Mancini; Executive Committee: W. Weintraub (Chair), W. Boden, R. O’Rourke, K. Teo, P. Hartigan, M. Knudtson, D. Maron, E. Bates, A. Blaustein, D. Booth, R. Carere, S Ellis, G. Gosselin, G. Gau, A. Jacobs, S. King, III, W. Kostuk, C. Harris, J. Spertus; P. Peduzzi (ex-officio); Data and Security Supervisory Commission: T. Ryan (Chair), B. Turnbull, T. Feldman, R. Bonow, W. Haskell, P. Diehr, P. Lachenbruch, D. Waters, D. Johnstone; Selection committee : L. Cohen (chair), B. Cantin, W. Hager, F. Samaha, J. Januzzi, J. Arrighi, B. Chaitman; Economic Committee: W. Weintraub (Chair), P. Hartigan, R. O’Rourke, W. Boden, P. Barnett, J. Spertus, R. Goeree; Optimal Medical Therapy Committee: D. Maron (chairman), W. Boden, R. O’Rourke, K. Teo, W. Weintraub.

The following members assisted in the coordination of the study: VA Cooperative Studies Program Coordinating Center, VA Connecticut Health System, West Haven, CT – P. Peduzzi (director); Mr. Antonelli, (Associate Director of Operations); J. Smith (project manager); R. Kilstrom, B. Hunter (coordinators); L. Durant (Quality Assurance Manager); S. O’Neil (Endpoints Coordinator); T. Economou, J. Nabors (programmers); A. Kossack (data clerk); VA Cooperative Studies Program Clinical Research Pharmacy Coordinating Center, Albuquerque, NM – M. Sather (Director), C. Harris (Deputy Director), W. Gagne (Project Leader), C. Fye (Pharmacist ); VA Cooperative Studies Human Rights Committee, West Haven, CT — R. Marottoli (Chair), H. Allore, D. Beckwith, W. Farrell, R. Feldman, R. Mehta, J. Neiderman, E. Perry, S. Kasl , Mr. Zeman; VA Office of Research and Development, Clinical Science Research and Development, Washington, DC — T. O’Leary (Acting Director), G. Huang (Deputy Director, Cooperative Studies Program); Offices of Study Chairs – Western New York VA Healthcare Network and Buffalo General Hospital–SUNY, Buffalo, NY – W. Boden (Study Co-Chair), M. Dada, K. Potter (National Coordinators), T. Rivera (program assistant); South Texas Veterans Health Care System, San Antonio, TX – R. O’Rourke (Study Co-Chair), P. Casperson (National Coordinator), A. O’Shea (Program Assistant); McMaster University Medical Center, Hamilton, ON, Canada — K. Teo (study co-chair), G. Woodcock (coordinator); Laboratories: Christiana Care Center for Outcomes Research, Newark, DE, and Emory University, Atlanta — W. Weintraub; Health Economics Research Center, Menlo Park, CA — P. Barnett; Health Technology Assessment Program, Hamilton, ON, Canada — R. Goeree, B. O’Brien; Vancouver Hospital, Core Cardiovascular Imaging Research Laboratory, Vancouver, British Columbia, Canada — GBJ Mancini, E. Yeoh; Central Lipid Core Laboratory at Washington University, St. Louis – J. Ladenson, V. Thompson; Saint Louis University ECG Basic Laboratory, Saint Louis – B. Chaitman, T. Bertran; Nuclear Core Laboratory at Cedars-Sinai Medical Center, Los Angeles – D. Berman, J. Gerlach, R. Littman, L. Shaw; San Diego State University PACE Program, San Diego, CA – K. Calfas, J. Sallis.

The following investigators are listed according to their clinical study sites: VIRGINIA: South Texas Veterans Health Care System, San Antonio, TX — R. O’Rourke, P. Baker, J. Bolton; VA Medical Center, Houston — A. Blaustein, C. Rowe; VA Medical Center, Durham, North Carolina — K. Morris, S. Hoffman; VA Health Care System, New York — S. Sedlis, M. Keary; VA Health Care System, Ann Arbor, MI — C. Duvernoy, C. Majors; VA Medical Center, Lexington, KY — Booth, Mr. Shockey; James A. Haley Veterans’ Hospital, Tampa, Florida — R. Zoble, I. Fernandez; VA Health Care System, Puget Sound, WA — K. Lehmann, A. Sorley, M. Abel; VA Health Care System, Albuquerque, New Mexico — M. Sheldon, K. Wagoner; Portland VA Medical Center, Portland, OR — E. Murphy, K. Avalos; Iowa City VA Medical Center, Iowa City — J. Rossen, K. Schneider; Central Arkansas Veterans Health Care System, Little Rock, AR — B. Molavi, L. Garza, P. Barton; VA Medical Center, Atlanta — K. Mavromatis, Z. Forghani; Tennessee Valley Health System, Nashville — R. Smith, C. Mitchell; VA Medical Center, Memphis, TN — K. Ramanathan, T. Touchstone. Canada: London Health Sciences Centre, London, Ont. — W. Kostuk, K. Sridhar, S. Carr, D. Wiseman; Sudbury Regional Hospital, Sudbury, ON — S. Nawaz, C. Dion; Montreal Heart Institute, Montreal — G. Gosselin, J. Théberge, M. Cuso; Queen Elizabeth II Health Care Centre, Halifax, NS — L. Title, P. Simon, L. Carroll, K. Courtney-Cox; Sunnybrook Health Center, Toronto — E. Cohen, E. Hsu; University Health Network – Toronto Hospital, Toronto — V. Dzavik, J. Lan; Foothills Hospital, Calgary, Alta. — M. Knudtson, D. Lundberg; Hamilton General Hospital – McMaster Clinic, Hamilton, ON — M. Natarajan, G. Cappelli; St. Michael’s Hospital, Toronto — M. Kutryk, A. DiMarco, B. Strauss; Vancouver Hospital, Vancouver, BC — A. Fung, J. Chow; Saint John Regional Hospital, Saint John, N.B. — D. Marr, F. Fitzgerald; St. Paul’s Hospital, Vancouver, BC — R. Carere, T. Nacario; University of Alberta Hospital, Edmonton — W. Tymchak, L. Harris; Trillium Health Care, Newmarket, Ontario — C. Lazzam, A. Carter; Montreal Sacred Heart Hospital, Montreal — D. Palisaitis, C. Mercury. US non VA: Mayo Clinic, Rochester, MN — Mr. Bell, Mr. Peterson; MIMA Century Research Associates, Melbourne, Florida —R. Vicari, Mr. Carroll; University of Michigan Medical Center, Ann Arbor — E. Bates, A. Luciano; Kaiser Permanente Medical Group of Southern California, California —P. Mahrer; S. Reyes; University of Oklahoma, Oklahoma City — J. Saucedo, D. van Wieren; Mid America Heart Institute, St. Louis — J. O’Keefe, P. Kennedy; Boston Medical Center, Boston — A. Jacobs. C. Berger, S. Mayo; Emory University Hospital, Atlanta — J. Miller, T. Arnold; Hartford Hospital, Hartford, CT — F. Kiernan, D. Murphy; Henry Ford Health System, Detroit — A. Kugelmass, R. Pangilinan; University of Rochester Medical Center, Rochester, NY — R. Schwartz, L. Caufield; Vanderbilt University Hospital, Nashville — D. Hansen, C. Mitchell; SUNY University Hospital, Syracuse, NY — R. Carhart, A. Pennella; Cleveland Clinic, Cleveland — S. Ellis, C. Stevenson; Barnes – Jewish Hospital, St. Louis — R. Krone, J. Humphrey; Mayo Clinic, Scottsdale, AZ — C. Appleton, J. Wisbey; Christiana Care Health Systems, Wilmington, DE — M. Stillabower, A. DiSabatino; Rush–Presbyterian–St. Luke’s Medical Center, Chicago — Mr. Davidson, J. Mathien.