Medical therapy

Endoscopic sinus surgery with effective medical therapy for chronic rhinosinusitis with nasal polyps

Patients with chronic rhinosinusitis with nasal polyps were found to benefit more from the combination of endoscopic sinus surgery and medical treatment compared to medical treatment alone, although the minimal clinically important difference was not reached. According to the results of a study published in Respiratory Medicine The Lancet. Typically performed when patients with CRSwNP […]

Medical treatment

Comparing catheter ablation on difficult outcomes versus medical treatment for patients with atrial fibrillation: a meta-analysis of randomized controlled trials with trial sequential analysis

This article was originally published here PLoS One. 2022 Jan 19;17(1):e0262702. doi: 10.1371/journal.pone.0262702. eCollection 2022. ABSTRACT BACKGROUND: The prevailing opinion is that ablation does not reduce the incidence of stroke and death in atrial fibrillation (AF), and guidelines suggest that long-term anticoagulation is needed after ablation , regardless of the success of the procedure. We […]

Medical therapy

Endoscopic sinus surgery with medical treatment versus medical treatment for chronic rhinosinusitis with nasal polyps: a multicenter, randomized, controlled trial

Fund Endoscopic sinus surgery (ESS) is a common operation in patients with chronic rhinosinusitis with nasal polyps (CRSwNP) when medical treatment alone is insufficient. No randomized controlled trials on the effectiveness of ESS have been published. Our aim was to assess the effectiveness of ESS plus medical treatment versus medical treatment alone in patients with […]

Medical therapy

optimal medical treatment in patients undergoing PVI

Persistent gaps in treatment practice remain for peripheral arterial disease (PAD) and atherosclerosis. Megan Lee, a fourth-year medical student at Yale School of Medicine, explores inconsistencies in the use of guideline-directed medical therapy after peripheral vascular intervention (PVI), a minimally invasive procedure that restores blood flow to the lower limbs. Published in the American Heart […]

Medical therapy

Endocrine Society Reading Room | The limited efficacy of medical therapy in primary aldosteronism

Primary aldosteronism or primary hyperaldosteronism (PA) is the excessive production of aldosterone by the zona glomerulosa of the adrenal glands resulting in secondary hypertension. Although initially thought to be a rare cause of secondary hypertension with a prevalence of 4.3 mmol/L with a median reference range of 3.5 to 5.0 mmol/L). Of the 155 patients […]

Medical therapy

Adding dapagliflozin to effective and cost-effective medical treatment in HFrEF

August 16, 2021 2 minute read Source/Disclosures Published by: Disclosures: Isaza does not report any relevant financial information. Please see the study for relevant financial information from all other authors. ADD A SUBJECT TO EMAIL ALERTS Receive an email when new articles are published on Please provide your email address to receive an email when […]

Medical therapy

HRS 2021: Early VT catheter ablation beats medical treatment in patients at risk of sudden death

Roderick Tung Results from the PAUSE-SCD trial show a significant reduction in the risk of recurrent ventricular tachycardia (VT), cardiovascular hospitalization and death when catheter ablation is used as an early first-line treatment for patients with structural heart disease. The PAUSE-SCD trial is the first VT ablation trial to include patients with non-ischemic cardiomyopathy and […]

Medical therapy

Software to Guide Medical Therapy in CI Earns FDA Breakthrough Device Designation

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Medical therapy

Optimizing medical therapy before clip repair for MR? ‘It’s hard’

Ensuring that patients receive maximum doses of heart failure treatments within guidelines is important, but also challenging, experts say. MIAMI, FL—A debate at TVT 2021 last week was supposed to focus on whether guideline-directed medical treatment should be tried at maximum tolerated doses before patients undergo transcatheter edge-to-edge repair (TEER ) for functional mitral regurgitation […]

Medical therapy

In high-risk patients, optimal medical therapy confers a survival benefit after PCI, CABG

Source/Disclosures Published by: Disclosures: Boden, Gersh and Kawashima do not report any relevant financial information. Please see the study for relevant financial information from all other authors. ADD A SUBJECT TO EMAIL ALERTS Receive an email when new articles are published on Please provide your email address to receive an email when new articles are […]

Medical therapy

Metabolic surgery may be more effective than medical therapy for long-term control of type 2 diabetes

1. The 10-year remission rates were significantly higher for Roux-en-Y gastric bypass (RYGB) and biliopancreatic diversion (BPD) than for medical treatment. 2. Patients in the BPD and RYGB groups had fewer diabetes-related complications. Level of evidence assessment: 1 (Excellent) Overview of the study: Compared to conventional therapy, metabolic surgery results in significant short-term improvements in […]

Medical therapy

Medical therapy for endometriosis

But for women who fail such treatment due to progesterone resistance or intolerance to these compounds, other options are needed. The Belgian authors selected 11 articles published from a literature search in the PubMed and Embase electronic databases up to December 2020. The search was limited to peer-reviewed English full texts that reported data on […]

Medical therapy

Physical health, improved quality of life with bariatric surgery compared to medical therapy

April 26, 2021 1 minute read Source/Disclosures Published by: Source: Aminan A, et al. Patient-reported outcomes after metabolic surgery versus medical treatment for diabetes: insights from the STAMPEDE randomized trial. Presented at the American Surgical Association Annual Meeting; April 15-16, 2021 (virtual meeting). Disclosures: The authors report no relevant financial information. ADD A SUBJECT TO […]

Medical treatment

Medical treatment equal to invasive therapy for spontaneous coronary artery dissection

April 09, 2021 1 minute read Source/Disclosures Published by: Disclosures: The authors report no relevant financial information. ADD A SUBJECT TO EMAIL ALERTS Receive an email when new articles are published on Please provide your email address to receive an email when new articles are published on . ” data-action=”subscribe”> Subscribe We have not been […]

Medical therapy

10-year RCT analysis suggests metabolic surgery is best medical therapy for T2D control

Data from a follow-up analysis of a randomized controlled trial suggest that weight loss surgery may be a more effective strategy than conventional medical therapy for the long-term control of type 2 diabetes. A 10-year follow-up to a trial comparing metabolic surgery to medical therapy in patients with type 2 diabetes, findings suggest metabolic surgery […]

Medical therapy

Medical therapy may prevent strokes in asymptomatic carotid stenosis

August 13, 2020 2 minute read Source/Disclosures Published by: Disclosures: Keyhani does not report any relevant financial information. Please see the study for relevant financial information from all other authors. ADD A SUBJECT TO EMAIL ALERTS Receive an email when new articles are published on Please provide your email […]

Medical therapy

Carotid endarterectomy and medical therapy show similar efficacy in asymptomatic carotid stenosis

1. In patients with asymptomatic carotid stenosis, there was no significant difference between the comparative effectiveness of initial medical therapy versus carotid endarterectomy. 2. The absolute risk reduction was found to be less than half the difference in risk of fatal and non-fatal strokes from carotid endarterectomy compared to 20 years ago. Level of evidence […]

Medical therapy

EXCEL Deep Dive: Repeated revascularization, medical treatment and anemia all impact patient prognosis

A session devoted to the study of ICP versus CABG for left trunk disease provides an understanding of what influences clinical outcomes after the procedure. SAN DIEGO, CA—A deep dive into the EXCEL test at TCT 2018 provided some information on the impact of various clinical and patient characteristics, including postoperative medical treatment, baseline anemia, […]

Alternative medicine

The conflict between alternative medicine and medical science dates back to the 19th century

Medicine today is a highly specialized science, advanced by expensive laboratory research published in reputable scientific journals, following strict criteria of scientific evidence. Meanwhile, unorthodox or alternative medicine thrives on divergent theories, which more or less conflict with orthodox medicine. This division dates back to the 19and century, where the central themes of the modern […]

Medical therapy

“Reasonable option” medical therapy vs surgery in Cushing’s disease

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Medical treatment

How to measure the potential harm of medical treatment

As we wrote last week, far fewer people benefit from medical therapies than we tend to think. This fact is quantified in the number of therapies needed to treat, or NNT, which tells you how many people would need to receive medical therapy for one person to benefit. NSTs well above 10 or even 100 […]

Medical therapy

Optimal medical therapy with or without PCI for stable coronary artery disease

The authors’ affiliations are as follows: Western New York Veterans Affairs (VA) Healthcare Network and Buffalo General Hospital–SUNY, Buffalo, NY (WEB); South Texas Veterans Health Care System – Audie Murphy Campus, San Antonio, TX (RAO, PC); McMaster University Medical Center, Hamilton, ON, Canada (KKT); VA Cooperative Studies Program Coordinating Center, VA Connecticut Health System, West […]